A baby with DNA from three people has been born in Greece following a controversial fertility treatment. “The doctors behind the treatment, from Greece and Spain, say it marks a historic advance — it is the first time an in vitro fertilization (IVF) technique involving DNA from three people has been used with the aim of addressing fertility problems,” reports The Guardian. From the report: The experimental IVF treatment, known as mitochondrial donation, involves using an egg from the mother, sperm from the father and another egg from a female donor. The vast majority of a person’s genes — about 99.8% — are found on the 23 pairs of chromosomes that sit inside the nucleus in each cell in the body, and in the IVF procedure this DNA comes from the two parents. However, a tiny proportion of genetic material also resides in a cell’s mitochondria, small structures that act as the cell’s batteries and float around freely in the cell body. In mitochondrial donation, the mother’s mitochondria are removed from her egg and replaced by a donor’s. The treatment was originally developed as a treatment that could prevent women with debilitating or even fatal mitochondrial diseases from passing them on to their children. The doctors behind the latest treatment claim that mitochondria also play a role in successful pregnancy and suggest that the technique could be applied more broadly as a fertility treatment. The 32-year old woman in the latest case had previously undergone four unsuccessful rounds of IVF.
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Source: https://science.slashdot.org/story/19/04/13/0554253/baby-with-dna-from-three-people-born-in-greece?utm_source=rss1.0mainlinkanon&utm_medium=feed